Paper of the week 22.02.19: Efficacy and safety of statin therapy in older people


Reference: Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials. This week’s paper of the week is brought to you by Professor Sir Muir Gray, 3V’s Founding Director. Bottom line, chosen by Muir from the paper Statin therapy has been shown to reduce major vascular events and vascular mortality in a wide range of individuals, but there is uncertainty about its efficacy and safety among older people… Statin therapy produces significant reductions in major vascular events irrespective of age, but there is less direct evidence of benefit among patients older than 75 years who do not already have evidence of occlusive vascular disease. This limitation is now being [...]